What is High-Sensitivity C-Reactive Protein?
hs-CRP is a protein produced by the liver in response to inflammation anywhere in the body. It is measured via a high-sensitivity blood test and is a widely used biomarker for systemic inflammatory status.
Why It Matters
Elevated hs-CRP has been consistently linked to periodontal disease. It also reflects the oral-systemic connection — chronic oral inflammation can raise systemic inflammatory markers, increasing cardiovascular and metabolic disease risk.
What Elevated Levels Mean
Elevated hs-CRP may indicate oral inflammation contributing to systemic inflammatory burden. However, it is not specific to oral disease — other conditions can also raise hs-CRP.
What To Do Next
Your dental and medical providers should collaborate to identify the sources of inflammation. Treating periodontal disease often reduces hs-CRP levels.
Related Biomarkers
This information is for educational purposes only and does not constitute medical advice. Always consult your dental provider for interpretation of your specific results.